Open access
Jul 2026
Integrating network pharmacology, molecular docking, and experimental validation to investigate the therapeutic effects and potential mechanisms of lycopene against pancreatic ductal adenocarcinoma
Background Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive tumor of the digestive system with a very low five-year survival rate. The limited efficacy and significant toxicity of existing chemotherapy regimens make the development of novel natural therapeutic agents an urgent priority. Lycopene is a...
Shaoyang Huang, Dandan Gu, Dan Song et al.
· Frontiers in Nutrition · 0 citations