Combined Letrozole and Growth Hormone Therapy in Late-Pubertal Males with Advanced Bone Age and Open Knee Physes
Highlights What are the main findings? In this single-arm retrospective study, combined letrozole and growth hormone therapy was associated with a mean gain of 6.58 ± 3.46 cm in final adult height relative to baseline predicted adult height in late-pubertal males with BA 15 –< 18 years and open knee physes (p < 0.001)....