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Open access Sep 2026

Comparative associations of cumulative cholesterol-HDL-glucose index and triglyceride-glucose index with risk of cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: a prospective cohort study

The American Heart Association recently introduced Cardiovascular-kidney-metabolic (CKM) syndrome as an integrated clinical construct. Evidence based on a single assessment suggests that the novel composite biomarker, Cholesterol, High-density lipoprotein, and Glucose (CHG) index, is associated with cardiovascular...

Jiabaili Wang, Qian Liu, Meng-Hui Li et al. · 0 citations
Open access Aug 2026

Cumulative lipid–inflammatory indices and the risk of cardiometabolic multimorbidity: a prospective cohort study

Background Cardiometabolic multimorbidity (CMM) has become a major global public health challenge. Although dyslipidemia and chronic low-grade inflammation are known to contribute to cardiometabolic diseases, their long-term cumulative combined effects on the risk of CMM remain poorly understood. This study aimed to ev...

Li-Jun Meng, Hai-Bo Gao, Jing Yang et al. · 0 citations

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