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Yupeng Wang

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Clinical trial Open access Aug 2026

T cell receptor repertoire dynamics and newly identified functional regulators of autologous tumor-infiltrating lymphocyte therapy in advanced solid tumors

The efficacy of TIL therapy in diverse solid tumors among Asian patients is demonstrated, dynamic TCR clonal remodeling in responders is revealed, and ASS1 and CEP20 knockout as strategies to potentiate antitumor activity are identified.

Fen-Ge Li, Ji-Long Yang, Gregory A. Lizee et al. · 0 citations

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