Dendrobine’s mechanism: alleviating cholesterol metabolism disorders via FXR/LXR modulation in NAFLD mouse livers
Cholesterol homeostasis is tightly regulated through hepatic synthesis, intestinal absorption, and biliary excretion, with bile acids serving as critical regulators of cholesterol catabolism. Dysregulated cholesterol metabolism and bile acid imbalance are hallmarks of non-alcoholic fatty liver disease (NAFLD), co...