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Author

Yusuke Kurihara

1 paper indexed here

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Open access Aug 2026

Development and Preclinical Evaluation of a Novel PET Probe for Phosphodiesterase 7B Imaging in Brain.

Phosphodiesterase 7B (PDE7B) is involved in the cAMP-PKA signaling pathway and has been implicated in neurodegenerative disorders. Accordingly, PDE7B represents a promising target for the development of therapeutics to treat such diseases. Recent efforts have led to the discovery of pyrimidinone-based compounds with hi...

T. Yamasaki, Zhi-Wei Xiao, Masayuki Fujinaga et al. · 0 citations

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