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Author

Yuto Nakajima

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Sep 2026

Plasma-Derived Factor VIIa/Factor X Improves Thrombin Generation Potential in a Plasma Model of Haemophilia A Supplemented With Direct Oral Anticoagulants.

BACKGROUND Patients with haemophilia (PwH) complicated with atrial fibrillation require direct oral anticoagulants (DOACs) to prevent thrombosis, but still require haemostatic management to control bleeding. However, specific recommendations for managing bleeding in PwH with inhibitors (PwH-inh) receiving DOACs remain...

Shigeharu Oh, Yuto Nakajima, Tomoko Onishi et al. · 0 citations
Review Sep 2026

Current perspectives on non-factor therapies for hemophilia.

Current and emerging non-factor therapies for hemophilia are summarized, focusing on their mechanisms of action, clinical evidence, safety considerations, unmet needs, and future perspectives for safe implementation in clinical practice.

Yuto Nakajima · 0 citations

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