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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Yutong Chen

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Open access Aug 2026

In vitro fertilisation and vitrification disrupt embryo mitochondrial function and redox balance that persists into adulthood in mice

Background and aims Assisted reproductive technologies (ART), including in vitro fertilisation (IVF), account for over 10 million births worldwide. ART-conceived young offspring show altered cardiovascular phenotypes, including cardiac remodelling and raised blood pressure, but the mechanisms remain unclear. Mitochondr...

Yutong Chen, Henrietha N Chukwuefe, M. Zi et al. · 0 citations
Open access Aug 2026

Type I PRMTs Play a Role in Mammalian Embryonic Lineage Specification

Mammalian preimplantation development requires precisely coordinated lineage decisions to establish the trophectoderm (TE), inner cell mass (ICM), epiblast (EPI), and primitive endoderm (PrE). Glucose metabolism and epigenetic regulation are increasingly recognised as key determinants of lineage specification during pr...

Jinlong Qiu, Yutong Chen, P. Beltran-Alvarez et al. · 0 citations

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