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Author

Yuxuan Wang

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Open access Sep 2026

Matrine Alleviates Sepsis-Induced Acute Lung Injury by Reinforcing NQO1/SLC7A11/GPX4-Associated Anti-Ferroptotic Defenses and Attenuating NF-κB-Driven Inflammation

Background Sepsis triggers dysregulated systemic inflammation and multiple-organ dysfunction, with the lungs being particularly susceptible to injury. Sepsis-induced acute respiratory distress syndrome (ARDS) is mainly driven by TLR4/NF-κB-mediated hyperinflammation and alveolar macrophage activation. Matrine, a bioact...

Xue Chen, Min Yuan, Ting Huang et al. · 0 citations
Open access Jul 2026

Integrated Multi-Omics Identifies Core Molecular Targets in Cerebral Venous Sinus Thrombosis-Induced Brain Injury

By applying integrated multi-omics profiling to a modified rat model, this study systematically mapped the molecular landscape of CVST-induced brain injury and provided a basis for further investigation into the mechanisms underlying CVST and for the design of novel treatment approaches.

Xiaohong Qin, Haoran Lu, Zhibiao Chen et al. · 0 citations

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