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Author

Yuyang Zhou

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Review Open access Jul 2026

Antimicrobial peptides in anti-infective and immunomodulatory applications: Mechanisms, challenges, and emerging computational design.

This review examines how the diverse molecular mechanisms through which AMPs exert antimicrobial effects-including membrane disruption, intracellular targeting, and immunomodulation-are intrinsically linked to their structural diversity and ecological breadth and critically evaluates engineering strategies that improve...

Yan-Lin Wang, Ya-Qian Yang, Yuyang Zhou et al. · 0 citations
Jul 2026

A Scalable Pan-Genomic Pipeline for Annotation-Free Discovery of Species-Specific Markers: Application to Staphylococcus aureus

An open-source, annotation-independent pan-genomic pipeline featuring an overlapping sliding-window algorithm and a three-tier subtractive screening funnel successfully circumvents conventional gene-centric limitations, providing a generalizable computational strategy for target discovery across other high-priority bac...

Yu-Yang Zhou, Jiayi Wang, Jun-Hua Xiao et al. · 0 citations

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