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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Z. M. Zhigula

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Open access Aug 2026

Association of the ITGA4 rs1143674 polymorphism with subclinical atherosclerosis in patients with ulcerative colitis over 40 years of age

Background: Patients with ulcerative colitis (UC) have an increased cardiovascular risk due to chronic inflammation and endothelial dysfunction. The ITGA4 gene encodes the α4 integrin subunit, a key regulator of leukocyte adhesion to endothelium. The ITGA4 rs1143674 genetic variant has been associated with coronary ath...

Z. M. Zhigula, A. A. Zhilina, N. V. Lareva et al. · 0 citations

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