Open access
Oct 2026
Defined Extracellular Matrix Contexts Rewire 3D Breast Cancer Cell Models: Effects of Sulfated Hyaluronan in the Expression of Matrix Effector and Matrix-Based Cell Functional Properties
Background: Breast cancer progression is strongly influenced by tumor cell interactions with the extracellular matrix (ECM). Three-dimensional (3D) cell culture models provide more relevant systems for studying aspects of the tumor microenvironment (TME), including tumor architecture, matrix remodeling and cell-ECM com...
Marios Vetoulas, Maria Drosinou, Nikoleta Alexiou et al.
· Cancers · 0 citations