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Z. Rattray

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Review Open access Aug 2026

Developing next-generation antibody-drug conjugates for breast cancer drug delivery: hurdles and advances in the clinic.

This review synthesizes literature spanning 1990-2026 on advances in ADC design and their clinical and translational implementation in breast cancer to support reframing antigen selection as a system-level challenge, supported by delivery-focused engineering, precision-medicine-driven trial design, and adaptive methodology.

Callum Chapman, A. Cheung, G. B. Armstrong et al. · 0 citations