Phage-directed precision microbiome medicine: engineering pathobiont depletion, synbiotic succession, microbial-function editing, metabolite host signaling, neurophagomics, and durable ecological state control in gut dysbiosis associated diseases
Bacteriophages are being investigated as strain-selective tools for modifying intestinal microbial communities, but the evidence supporting ecological reconstruction is substantially less mature than the evidence supporting targeted bacterial depletion. This review separates current knowledge into three domains: esta...