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Review Open access Oct 2026

Waiting for Trial Evidence or Using Real-World Evidence: Trade-Offs for Coverage with Evidence Development.

A decision-analytic framework is developed that extends value-of-information methods by incorporating an explicit bias parameter to capture structural distortion in RWE treatment effect estimates and quantifies the probability of RCT-based  CED dominance.

Bo-Shen Jiao, Yi-Zhi Liang, Li-Yuan Tao et al. · 0 citations

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