Author

Z. Zolkipli-Cunningham

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Review Open access Sep 2026

Advances in diagnosis of mitochondrial dysfunction and primary mitochondrial disease.

Mitochondria are critical cellular organelles engaged in energy production, diverse intermediary metabolic functions and signaling. Inherited genetic disorders directly affecting mitochondrial structure and/or function, known collectively as primary mitochondrial diseases, are among the most complex and heterogeneous i...

M. Kose, E. McCormick, J. Peterson et al. · Disease Models & Mechanisms · 0 citations

Review Open access Sep 2026

Endothelial–mitochondrial coupling in mitochondrial disease: A systematic review and quantitative synthesis of vascular, biochemical, and oxidative bioenergetic dysfunction

Improvements in endothelial function and NO synthesis following l-arginine or l-citrulline supplementation are consistent with a role for impaired endothelial NO signaling in the vascular manifestations of mitochondrial disease.

J. A. Adams, Tiffany S. Ko, Laith R. Sultan et al. · Therapeutic Advances in Rare... · 0 citations