Open access
Oct 2026
Epigenetic maintenance of PRC2-repressed chromatin requires RTT109 but not H3K56 acetylation.
In animals, plants, and some fungi, Polycomb Repressive Complex 2 (PRC2) catalyzes trimethylation of histone H3 lysine 27 (H3K27me3) to establish transcriptionally repressed chromatin. Here, we identify the histone acetyltransferase RTT109 as a key regulator of PRC2-repressed domains in the model fungus Neurospora cras...
Rochelle E. Yap, Felicia Ebot-Ojong, Abigail J. Ameri-Solanky et al.
· PLoS Genetics · 0 citations