Pathological microbial niches in diabetic foot ulcers: a host-microbe framework for impaired repair and niche-based stratification
Diabetic foot ulcers (DFUs) are commonly described through the clinical triad of hyperglycaemia, ischaemia and infection. That language is useful for bedside decision-making, but it does not fully explain why some wounds remain inflamed and open despite debridement, offloading, antimicrobial therapy, vascular assessmen...