Chronic non-healing wounds remain a major clinical challenge, with limited therapeutic efficacy and a huge burden on patients. Nanozymes have emerged as promising bioactive platforms for wound repair by modulating reactive oxygen species, immune responses, angiogenesis, and antimicrobial defense. However, traditional n...
Duo-Cui Yang, Ze-Hang Zheng, Han Wang et al.· Bioactive Materials· 0 citations
mTORC2, defined by its core component RICTOR, is a key regulator of immune cell function and inflammation, yet its roles have long been underappreciated due to lack of specific inhibitors and in vivo tools. This review summarizes the current understanding of mTORC2-specific signaling (via AKT, SGK1, and PKC) in regulat...