MnPt@metal organic framework nanozyme with photothermal/catalytic dual-strategy enhances Zn2+-mediated immunotherapy through activating pyroptosis and cGAS-STING pathway
Zinc ions (Zn2+) can induce immune response through activating pyroptosis and cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, and disrupting the intracellular redox balance is an important strategy for enhancing Zn2+-driven immunotherapy. Herein, using bimetallic manganese platinum (MnP...