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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Ze-Lin Wei

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Open access Aug 2026

Nucleosomes and IDRs suppress promiscuous GCN4 binding on minichromosomes

Eukaryotic sequence-specific transcription factors (TFs) must find their cognate DNA targets hidden in genomic chromatin amid an excess of nonspecific sequences and degenerate motifs. Although static TF interactions with nucleosomal targets have been elucidated, how TFs efficiently search for cognate sites within nativ...

Ze-Lin Wei, Oluwakemi E. Abiodun, Y. Ling et al. · 0 citations

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