BACKGROUND
Multiple studies have demonstrated that circulating tumor DNA (ctDNA), a component of liquid biopsy, exhibits strong performance in predicting prognosis across various types of tumors. However, its role in predicting prognosis among gastric cancer patients undergoing treatment remains inconclusive. Therefore...
Yu-Ze Liu, Yan-Li Liu, Dan Liu et al.· European Journal of Surgical...· 0 citations
Background Human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC) is characterized by high malignancy and a poor prognosis. Trastuzumab is the first-line targeted therapy for this disease, but the frequent development of primary and acquired resistance severely compromises treatment efficacy and i...
Qiang-Zu Shao, Fan Zhang, Wen-Jie Wang et al.· Translational Cancer Researc...· 0 citations
Mounting evidence implicates long non-coding RNA cancer susceptibility candidate 19 (CASC19) in the pathogenesis of diverse malignancies. However, its functional role and molecular mechanisms in gastric cancer (GC) remain elusive. Herein, we identified a novel 717-bp transcript isoform of CASC19 in GC cells. This study...