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Ze-Shan Yao

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Review Open access Sep 2026

Roles of glycolytic and pyruvate metabolism enzymes in Alzheimer’s disease glycometabolic reprogramming and their therapeutic potential

Current evidence regarding the dysregulation of major glycolytic and pyruvate-metabolizing enzymes, including hexokinase (HK), phosphofructokinase-1 (PFK1), pyruvate kinase (PK), lactate dehydrogenase (LDH), and the pyruvate dehydrogenase complex (PDHc), in both neurons and glial cells are synthesized.

Min-Min Chen, Chang-Min Zuo, Run-Zhi Li et al. · 0 citations

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