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Open access Aug 2026

LRRN4 Upregulates the IL23A-JAK2-STAT3 Signaling Axis and Drives Colorectal Cancer Metastasis.

In colorectal cancer (CRC), metastasis drives fatalities, necessitating the discovery of therapeutic targets modulating its progression. Though the secreted protein-coding gene leucine-rich repeat neuronal 4 (LRRN4) was shown to be highly overexpressed in CRC and linked to decreased survival in the analysis of TCGA-CRC...

Jia-Tian Lin, Shasha Min, Ze-Song Li et al. · 0 citations

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