Ze-Xin Zhao

Lateralized Tenm4 expression biases visual performance and modulates axonal growth and pre-synapse size in retinal ganglion cells

It is shown that the synaptic adhesion molecule Teneurin-4 (Tenm4) is expressed by RGCs and their postsynaptic tectal cell targets in a left-right side-specific manner in zebrafish, demonstrating that tenm4 plays an important role in sensorimotor circuit assembly, extending to neural activities and visual acuity.