Review
Sep 2026
TP53/p53 alterations in thyroid cancer: dedifferentiation, radioiodine refractoriness and risk stratification.
Most thyroid cancers are differentiated tumours with favourable outcomes, but a clinically important minority develops invasion, distant metastasis, loss of radioiodine uptake and histological dedifferentiation. TP53 encodes p53, a tumour suppressor that coordinates DNA-damage responses, cell-cycle arrest, apoptosis an...
Yang Shi, Jia-Peng Huang, W. Dong et al.
· Critical reviews in oncology... · 0 citations