Author

Zelin Chai

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Open access Aug 2026

Mitochondrial RNA as a broad-spectrum DAMP coordinates antiviral and damage-related immune clearance and confers therapeutic potential

The findings establish the mtRNA-MAVS axis as a central, broadly applicable immune surveillance pathway and provide a mechanistic framework for developing therapies that overcome both viral immune evasion and the limitations of current STING-targeted agonists.

Mingfu Tian, Guangli Li, Zelin Chai et al. · Cell Death & Disease · 0 citations