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Zeng-Jun Ren

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Open access Sep 2026

Single-cell multi-omics dissects transcript isoform and immune repertoire dynamics in human immunosenescence.

Immunosenescence, a major hallmark of systemic aging, refers to the progressive functional decline of the immune system. This decline not only compromises host defense and immunological memory but also fuels chronic inflammation and tissue degeneration (collectively known as inflammaging). While single-cell RNA sequenc...

Yu-Hui Zheng, Zeng-Jun Ren, Ya-Fei Yang et al. · 0 citations
Review Open access Jul 2026

Single-cell long-read transcriptomics: from technologies to biological insights

This review examines the experimental and computational foundations of scLR-seq, including platform selection, library design, cell barcode and unique molecular identifier recovery, transcript discovery, and isoform quantification, and summarize emerging insights into isoform usage, alternative splicing, transcription...

Zeng-Jun Ren, Wen-Teng Liu, Jian-Hua Yin et al. · 0 citations

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