Open access
Sep 2026
Determination of Bongkrekic Acid and Iso-Bongkrekic Acid in Red Yeast Rice and Its Related Products by Liquid Chromatography-Tandem Mass Spectrometry
Bongkrekic acid (BA) is a metabolite that is lethal to humans and is produced by Burkholderia gladioli pathovar cocovenenans (BGC) containing the bon gene cluster. An analytical method for BA and its stereoisomer, iso-bongkrekic acid (IBA), was established for deeply fermented rice products, such as red yeast rice and...
Yuan-Qiong Guo, Yu-Xin An, Jiao-Jiao Xu et al.
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