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Zerong Li

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Open access Aug 2026

Integrative multi-omics reveals a prognostic and therapeutic landscape of synthetic lethality-associated signatures in lung adenocarcinoma

Summary Lung adenocarcinoma (LUAD) exhibits considerable heterogeneity and therapeutic resistance. Here, we integrated single-cell RNA sequencing, spatial transcriptomics, and machine learning to characterize synthetic lethality (SL)-associated transcriptional activity in LUAD. We quantified SL activity across malignan...

Zerong Li, Wen-Mei Qiao, Bin Fan et al. · 0 citations

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