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Zhang-Li Peng

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Review Open access Sep 2026

Macrophage states and polarization during Mycobacterium tuberculosis infection: mechanisms, granuloma adaptation, and host-directed therapeutic opportunities

The molecular mechanisms underlying macrophage polarization during Mtb infection are synthesized, the bidirectional regulatory networks between pathogen-derived and host-derived factors are integrated, and their roles in immune evasion, granuloma biology, and emerging therapeutic strategies in tuberculosis are highligh...

Ming-Long Xu, Zhang-Li Peng · 0 citations

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