Sep 2026
Functionalized Spiky Microcarriers Orchestrate STING Activation and Durable Antitumor Immunity
The stimulator of interferon (IFN) genes (STING) pathway has garnered considerable attention due to its significant potential in anti-cancer effect. However, cyclic dinucleotides (CDNs), which are natural agonists or their derivatives for STING, are often hindered by their inherent properties of poor transmembrane pe...
Li-Ru Shang, Lin Peng, Zhang-Ping Huang et al.
· Molecular Pharmaceutics · 0 citations