Open access
Aug 2026
AbAgKer: a unified semi-supervised framework for antigen-antibody binding affinity and kinetics prediction
This work designs a biological prior-guided feature fusion framework that integrates pseudo-structural epitope knowledge and CDR-specific attention mechanisms via a mixture-of-experts architecture to effectively capture complex binding landscapes in antibody screening and drug residence time analysis.
G. Luo, Junkai Wang, Sizhe Zhang et al.
· Bioinformatics · 0 citations