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Author

Zhangsuo Liu

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Open access Aug 2026

USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease

It is demonstrated that impaired pexophagy drives peroxisomal dysfunction and tubular damage in DKD and a critical role of USP30 mediated regulation of pexophagy is revealed and suggested that USP30 may serve as an experimental intervention target to alleviate tubular injury in DKD.

Jia Li, Chaoyang Hua, Guang-Pu Li et al. · 0 citations
Open access Jul 2026

Structural basis of lipid-dependent allosteric gating mechanisms for PC1-PC2 ion channel

Lipid-dependent allosteric gating mechanism of the PC1-PC2 channel modulated by specific membrane lipids is revealed and multiple structural states showing how specific membrane lipids control channel opening are defined.

Mengying Chen, Zhifei Wang, Yan Shi et al. · 0 citations

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