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Zhao-Hong Wang

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Open access Aug 2026

ROS-Responsive siFGF19 Delivery Reprograms Pancreatic Stellate Cells and Remodels the Desmoplastic Microenvironment in Pancreatic Cancer

Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by extensive stromal fibrosis that limits drug delivery and promotes therapeutic resistance. Pancreatic stellate cells (PSCs), key mediators of desmoplasia, represent a promising yet underexploited therapeutic target. This study aimed to suppress PSC...

Zhao-Hong Wang, Sheng-zhang Lin, Su-Hua Zheng et al. · 1 citation

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