Zhao-Hua Guo

H3K18la facilitates nasopharyngeal carcinoma progression through the activation of the IGF2BP1-COX2 signaling pathway

Nasopharyngeal carcinoma (NPC) is a malignant tumor arising from the nasopharyngeal epithelial mucosa, with its development closely associated with metabolic reprogramming. Lactylation, an epigenetic modification induced by lactate, plays a regulatory role in gene transcription.The precise function and mechanisms of H3...