Author

Zhao Liang

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Open access Oct 2026

Albendazole induces ferroptosis through the USP7-GPX4 axis in B-cell acute lymphoblastic leukemia

B-cell acute lymphoblastic leukemia (B-ALL) is an aggressive hematological malignancy that still requires the development of novel therapeutic strategies. Here, leveraging a drug-repurposing strategy, we performed a high-throughput screen of 3008 U.S. Food and Drug Administration (FDA)-approved drugs and identified a...

Hao Wang, Tian-Wang Guan, Xiao-Nan Lin et al. · Communications Biology · 0 citations

Oct 2026

Toll-like Receptor 7 and Interferon-α Synergy Establishes a Positive Feedback Loop to Potentiate Antiviral Immunity in Chronic Hepatitis B.

BACKGROUND AND OBJECTIVES Current therapies for chronic hepatitis B (CHB) rarely achieve functional cure, underscoring the need for novel immunotherapies. Toll-like receptor 7 (TLR7), a key innate immune sensor, has emerged as a major drug development focus. This study aims to characterize stage-specific TLR7 expressio...

J. Ge, Zi-Xu Chen, Xuan Huang et al. · Antiviral Research · 0 citations