Open access
Sep 2026
An H2A.Z-dependent epigenetic checkpoint in macrophages couples genetic risk to microbial metabolite signaling.
H2A.Z deposition functions as an acylation-dependent epigenetic checkpoint that couples macrophage differentiation to inflammatory resolution, integrating host genetics and microbial metabolites to calibrate immune responses.
Zhao-Ran Sun, Fan-Yi Meng, Chun-Jian Piao et al.
· Protein & Cell · 0 citations