Zhao-Shuai Zhou

Ferroptosis-driven cell death perpetuates the chronic inflammatory cycle in periodontitis: a single-cell transcriptomic study

Background Periodontitis represents one of the most prevalent chronic inflammatory diseases, characterized by progressive periodontal tissue destruction driven by immune dysregulation. Emerging evidence establishes ferroptosis—an iron-dependent, lipid-peroxidation-driven form of regulated cell death—as a pivotal but un...