Methylparaben promotes colorectal tumor growth through nuclear receptor-mediated transcriptional reprogramming and inflammatory signaling: Evidence from integrated transcriptomics and network toxicology.
Methylparaben (MP) is a widely used preservative with potential endocrine-disrupting activity, but its role in colorectal cancer (CRC) remains unclear. This study integrated in vitro and in vivo experiments with transcriptomics, network toxicology, and molecular simulations to investigate MP's effects on CRC progressio...