Urinary Proteomics Enables Non-Invasive and Longitudinal Monitoring of Tumor Burden Dynamics and Early Recurrence in HCC.
PURPOSE To develop a non-invasive, urine-based approach for dynamic monitoring of tumor burden and early detection of recurrence in hepatocellular carcinoma (HCC), addressing the limited sensitivity of conventional serum biomarkers such as AFP and DCP, particularly for minimal residual disease (MRD) assessment. METHO...