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Zhaoyang Zhong

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Open access Sep 2026

Rbp-Jκ controls NK cell late maturation and migration via chromatin landscape remodeling

Significance Despite the established role of Rbp-Jκ as the master transcriptional regulator of Notch signaling, its cell-intrinsic functions in natural killer (NK) cells remain unknown. In this study, we integrate genetic ablation (Ncr1iCre × Rbp-Jκfl/fl) studies with scRNA-seq, scATAC-seq, bulk ATAC-seq, CUT&Tag, and...

Hongyan Peng, Yao Yang, Yongjie Liu et al. · 0 citations

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