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Zhaoyuan Meng

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Aug 2026

Reprogramming of lipid metabolism by PFKL promotes the adaptation of pancreatic ductal adenocarcinoma to glucose deprivation.

BACKGROUND/OBJECTIVE Lipid droplet (LD)-mitochondria tethering is essential for fatty acid oxidation (FAO), which sustains tumor cell survival under nutrient-deprivation conditions. However, how LD-mitochondria contact is regulated in pancreatic ductal adenocarcinoma (PDAC) is unclear. METHODS This study investigated...

Lu Chai, Zhaoyuan Meng, Zhi-Min Lu et al. · 0 citations

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