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Aug 2026

Engineered Exosome‐Mediated FIH‐1 Delivery for Targeted Therapy of Hyperuricemic Nephropathy by Inhibiting NF‐κB/NLRP3 Inflammasome Signaling and Restoring Autophagic Homeostasis

Renal tubular epithelial fibrosis is a key pathological process in the progression of hyperuricemia (HUA), and hyperuricemic nephropathy (HN). Targeted inhibition of renal tubular epithelial cell (RTEC) fibrosis represents a promising therapeutic strategy for HN. Extracellular vesicles derived from induced pluripotent...

Ting Xiao, Yu Liu, Zhe He et al. · 0 citations

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