G protein-coupled receptor 183 (GPR183), also known as EBI2, is a chemoattractant receptor whose principal endogenous ligand is 7α,25-dihydroxycholesterol (7α,25-OHC). Its expression varies dynamically across immune-cell subsets and activation states. By sensing local 7α,25-OHC gradients, GPR183 converts tissue metabol...
Xin-Rui Lin, Xin-Yu Dong, Zhe Jiang et al.· Frontiers in Immunology· 0 citations
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