Inflammatory bowel disease‑associated colorectal cancer (IBD‑CRC) arises in the setting of long‑standing chronic intestinal inflammation, in which immune dysregulation cannot be readily attributed to the dominance of a single inhibitory pathway or to global immunosuppression. Persistent inflammatory signaling sustains...
Tao Zhang, Zhe-Tan Ren, Ling Wang et al.· International Journal of Mol...· 0 citations
The pathogenesis of cholecystitis involves the complex interplay of bile stasis, microbial dysbiosis, metabolic disturbances, and immune responses. Gut microbiota-associated metabolites can modulate adaptive immune components, including T helper 17 (Th17) cells, regulatory T (Treg) cells, CD8+ T cells, and B cells, thr...
Xin-Qi Wang, Tao Zhang, Zhe-Tan Ren et al.· Frontiers in Microbiology· 0 citations
Although not possessing the highest AUC, the SVM demonstrated exceptional resistance to overfitting, evidenced by a minimal AUC decrement of merely 0.0298 from the training to the validation set, underscoring its tangible clinical utility.
Shuai Pang, Hao Dong, Zhe-Tan Ren et al.· Frontiers in Oncology· 0 citations
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