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Jul 2026

Shared Genetic Architecture of Epilepsy and Glioma Revealed by Mendelian Randomization: Identifying Prognostic Biomarkers and Therapeutic Targets.

These findings support a neuroimmune model in which pleiotropic germline variants act via microglia and excitatory neurons to link seizure biology with tumor immunity and prognosis, and reveal a common genetic architecture between glioma and epilepsy.

Xiangling Feng, Jiahao Zhou, Zhen He et al. · 0 citations