DRCMDA: A Dual-View Drug Repositioning Framework with Cluster-Aware Structured Masked Reconstruction and Diffusion-Based Metapath-Graph Augmentation.
Drug repositioning aims to identify new therapeutic indications for existing drugs, yet current deep learning approaches on multi-source biological data face limitations in both homogeneous and heterogeneous network modeling. In homogeneous similarity networks, random masking-based self-supervised learning neglects int...