Oct 2026
Quinoline-Based Amide Foldamers with One-Handed Chirality Induced by an Asymmetric Plane
A quinoline-containing cyclophane derivative with planar chirality was rationally designed and synthesized based on [2.2]paracyclophane (PCP) and used as a structural unit to induce the absolute one-handed helical conformation of quinoline foldamers. 1H NMR, X-ray crystal diffraction, and chiral HPLC studies demonstr...
Grace Victoria Poo, Kai-Yue Liu, Yu-Ping Wu et al.
· Organic Letters · 0 citations