Author

Zhen-Jie Wang

2 papers indexed here

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Review Open access Aug 2026

Metabolite-driven protein modifications in immune signaling: from established principles to emerging pyruvylation

The conceptual framework of metabolite-driven protein modifications is summarized, established marks are compared, and remaining questions surrounding pyruvylation chemistry, enzyme and substrate specificity, reader mechanisms, compartmentalization, detection strategies, physiological relevance, and potential immunopha...

Zi-Ye Zhang, Ming-Ze Xu, Sen Zhang et al. · Frontiers in Immunology · 0 citations

Open access Aug 2026

Optimizing vancomycin therapy: the critical role of dosing frequency, AUC monitoring and gender: a retrospective cohort study.

Background Optimizing vancomycin therapy requires balancing efficacy and toxicity. Although therapeutic drug monitoring (TDM) guided by area-under-the-curve (AUC) measurements is now recommended, the effect of dosing frequency and patient-specific factors remain underexplored. This study examined the relationships of d...

Naiju Zhang, Yi Li, Long-Yun Chen et al. · Frontiers in Pharmacology · 0 citations